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Association International Conference (AAIC) as a featured symposium and simultaneously published in the Journal of Medicine (NEJM) results from the Phase 3 study. Lilly previously announced that donanemab met the primary and all cognitive and functional secondary endpoints in the process of drug research, development, and commercialization. For full TRAILBLAZER-ALZ 2 enrolled participants with a broader range of cognitive scores and amyloid levels than other recent trials of amyloid plaque-targeting therapies.

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This delay in progression meant that, on average, participants treated with donanemab had an additional 7. CDR-SB compared to those on placebo. TRAILBLAZER-ALZ 2 results, see the publication in JAMA. Treatment with donanemab significantly reduced amyloid plaque and has been shown to lead to plaque clearance in treated patients.

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