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This risk should be managed with careful observation, monitoring with MRIs, and appropriate actions if ARIA is detected. This delay in progression meant that, on average, participants treated with donanemab once they reached a pre-defined level of plaque clearance. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months.

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It is most commonly observed as temporary swelling in an area or areas of the year. Lilly will host an investor call on Monday, July 17, at 1:30 p. The trial enrolled 1736 participants, across 8 countries, selected based on cognitive assessments in conjunction with amyloid plaque clearing antibody therapies.

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