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Please see Full Prescribing Information for additional safety information. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell death. It will be reported once the predefined number of survival events has been reported in post-marketing cases.

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Important Safety InformationXTANDI (enzalutamide) is an androgen receptor signaling inhibitor. No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC).

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