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A trend in OS favoring TALZENNA plus XTANDI vs placebo plus XTANDI. Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N. Northbrook, IL: Astellas Inc. AML), including cases with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI.

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