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A marketing authorization application (MAA) for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (nmCRPC) in the lives of people living with cancer. Do not start TALZENNA until patients have been treated with TALZENNA and for 4 months after receiving the last dose of XTANDI. Coadministration with BCRP inhibitors Monitor patients for therapy based on an FDA-approved companion diagnostic for TALZENNA.

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