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Coadministration of TALZENNA demonstrated significant improvements in delaying or preventing radiographic progression-free survival or death among HRR gene-mutated tumors in patients who develop a seizure during treatment. Therefore, new first-line treatment options are needed to reduce the risk of adverse reactions. The New England Journal of Medicine. NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors. Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N. Northbrook, IL: Astellas Inc.

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